Prescription skincare, examined.Research checked October 7, 2026
SKIN
FIELD GUIDE

Explore a concern

Pigmentation

Products in a shared category may have different indications and safety requirements. A clinician determines whether a treatment fits your diagnosis.

Pigmentation

CoreAge Rx

Spot On

Hydroquinone, kojic acid and niacinamide; confirm individual strengths

Compounded topical
Pigmentation02

Musely

The Spot Cream

Variants include hydroquinone 6% or 12%; an HQ-free option uses azelaic acid 17% and tranexamic acid 4%. Other ingredients vary.

Compounded prescription
Pigmentation03

Musely

The Spot Pill

Tranexamic acid 225 mg in the current support-center description

Compounded prescription
Pigmentation04

Musely

The Spot Peel

BOOST lists azelaic acid 20% and tretinoin 0.01%; BURST lists hydroquinone 12% and tretinoin 0.01%. Supporting ingredients differ.

Compounded prescription
Pigmentation05

Musely

The Body Cream

Vanish: hydroquinone 12%, tretinoin 0.01%, glycolic acid 1%; Fade omits hydroquinone and lists glycolic acid 6%. A KP variant is also documented.

Compounded prescription
Pigmentation06

Musely

The Private Cream

Hydroquinone variants at 3%, 6% and 12%; TENDER instead lists tranexamic acid 6%. Niacinamide 2% accompanies the listed formulas.

Compounded prescription
Pigmentation07

Agency

Dark Spot Rx

Potential hydroquinone, azelaic acid, kojic acid, green tea extract, resveratrol and hydrocortisone; hydroquinone-free variants exist

Compounded topical
Pigmentation08

Likeness Rx

Dark Spot Cream

Hydroquinone 6%, kojic acid 6% and niacinamide

Compounded topical
Pigmentation10

Strut Health

Melasma Formula

Hydroquinone, hydrocortisone, kojic acid and tretinoin

Compounded topical
Pigmentation11

Skin Medicinals

Hyperpigmentation Compound

Hydroquinone options described at 4%, 8% and 12%; other formula details require confirmation

Compounded topical
Pigmentation13

Nurx

Dark Spots Formula

Azelaic acid 6%, kojic acid 6%, hydroquinone 4%, hydrocortisone 1%, tretinoin 0.05%

Compounded topical
Pigmentation14

Tri-Luma

Triple Combination Cream

Fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%

Manufactured prescription